This type of machine is designed for a wide range of bottle sizes in the pharmaceutical filling and packaging industry. In a range of about 50ml to 2000ml bottle formats can be selected conveniently via the HMI. Essential functions are automatically adjusted so that only a few format parts must be replaced. Machine parameters can be set validated and password protected on the HMI. Less mechanical movements and a direct suction at the blowing nozzels allow for clean room suitability to class ISO. 3 The performance of a 6-fold based machine is about 60 bottles from 50 to 250ml bottles per minute. With 2000ml volume there are still 15 bottles per minute. A ionizing system is integrated for plastic bottles in blown air stream. The machine design conforms to the EU Machinery Directive.